WebJan 26, 2015 · The IC 50 values were 114.1 and 50.6 μ M in Du145 and PC3 cells, respectively, indicating the synergistic effects of transfection of Pdcd5 and cisplatin treatment. Figure 3 Cell viability of Du145 and PC3 prostate cancer cells following transfection of Pdcd5. WebThese organometallic compounds demonstrate superior cytotoxicity against osteosarcoma and human breast cancer cells relative to cisplatin, a well-known chemotherapeutic …
Cisplatin remodels the tumor immune microenvironment via the
WebApr 10, 2024 · Triple-negative breast cancer (TNBC) is one of the most aggressive forms of breast cancer and constitutes 10–20% of all breast cancer cases. Even though … WebUsing MTT assay, IC50 values of cisplatin and 5‑fluorouracil were determined to be 14.2 and 8.9 µM for cisplatin and 5‑fluorouracil, respectively. The effects of different concentrations of cisplatin and 5‑fluorouracil in combination with two different concentrations of bortezomib were examined in the 4T1 cells. ca oh 2 ph value
Nab-paclitaxel for the treatment of triple-negative breast cancer ...
WebJun 22, 2024 · Cisplatin (DDP) was reported to improve pathological complete response (pCR) rates in triple-negative breast cancer (TNBC) patients, however, the molecular mechanism still remains largely unknown. Emerging evidence suggested that some chemotherapeutic drugs played anti-tumor effects by inducing cell pyroptosis. WebTriple-negative breast cancer (TNBC) is a highly aggressive type of breast cancer lacking estrogen receptor (ER), progesterone receptor (PR) and human epidermal growth factor2 (HER2), which resulted in the lack of target for treatment. 14 Up to date, drug treatment for triple-negative breast cancer still limited to cytotoxic agents such as ... WebMar 22, 2024 · The drug’s IC 50 values indicated that the cells had acquired a stable CDDP-resistance phenotype, with the IC 50 values of the A549/DDP cells remaining significantly higher than the parental A549... ca varun jain classes