Hydroxytamoxifen是什么
Web1 mrt. 1999 · Tissue. Treatment. Weight (g). a Female Sprague–Dawley rats (8 weeks old, 8 per group) were treated by gavage with seven daily doses of tamoxifen (20 mg/kg, 54 μmol/kg, dissolved in 200 μl tricaprylin), 4-hydroxytamoxifen (21 mg/kg, 54 μmol/kg, dissolved in 200 μl tricaprylin) or 200 μl tricaprylin alone. Twenty-four hours following the … Web3 mrt. 2012 · The antiestrogenic effect of tamoxifen is mainly attributable to the active metabolites endoxifen and 4-hydroxytamoxifen. This effect is assumed to be concentration-dependent and therefore quantitative analysis of tamoxifen and metabolites for clinical studies and therapeutic drug monitoring is increasing. We investigated the …
Hydroxytamoxifen是什么
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Web然而 他莫昔芬确会促进ER的AF1（Activation function 1）结构域的激活，促进微弱的转录激活，进而导致雌激素信号的不完全阻止 。. 在经过临床内分泌治疗后，乳腺癌细胞会发 … Web14 jan. 2024 · (E)-4-羟基他莫昔芬用途 (E)-4-Hydroxytamoxifen 是 (Z)-4-hydroxytamoxifen 的低活性异构体，是雌激素受体 (estrogen receptor) 调节剂。 产品性质 图谱 (E)-4-羟基他莫昔芬名称 (E)-4-羟基他莫昔芬生物活性 (E)-4-羟基他莫昔芬物理化学性质 (E)-4-羟基他莫昔芬合成线路 (E)-4-羟基他莫昔芬英文别名 4- [1- [4- [2- …
Web用(Z)-4-hydroxytamoxifen对已接受0 ~ 2 μg雌二醇皮下注射的未成熟大鼠灌胃。 与给予雌二醇的对照组比，这两种化合物与子宫湿重的减少呈剂量相关性。 以每天1 μg的剂 … Web23 mrt. 2005 · 4-Hydroxytamoxifen-Mediated Apoptosis in Multiple Myeloma Cells Requires a Mitochondrial-Dependent Death Pathway. It has been suggested that for one multiple myeloma cell line tamoxifen treatment induces an up-regulation of Fas expression and that tamoxifen-induced apoptosis requires the death receptor extrinsic pathway .
Web4-Hydroxytamoxifen is a selective estrogen receptor modulator (SERM). 体外活性. 4-Hydroxytamoxifen can inhibit the [3H]estradiol binding to the estrogen receptor (IC50: … http://www.luyor.cn/news/news2/tdtomato.html
Web天门冬酰胺，是一种有机化合物，化学式为c4h8n2o3，有d、l两种旋光异构体，主要用作药物，适用症状为降血压， 扩张支气管（平喘）, 抗消化性溃疡及胃功能障碍，也可用于 …
Web21 sep. 2024 · 4-Hydroxytamoxifen（单羟基三苯氧胺）是一种选择性雌激素受体拮抗剂， [3 H]雌二醇与雌激素受体结合的IC 50为3.3 nM 。. 4-Hydroxytamoxifen（10,100 nM） … how do people use the river nileWeb友情链接： 医学导航 医学百科 基因123 中华养生网 本站部分文字及图片均来自于网络，如有侵权及时通知我们，联系邮箱：[email protected] 医学导航 医学百科 基因123 中华 … how much ram does tb2t server haveWeb2 mrt. 2009 · Endoxifen is formed in the liver by the CYP2D6-mediated oxidation of NDT and CYP2D6 polymorphisms and drug-induced inhibition of CYP2D6 enzyme activity significantly reduce endoxifen concentrations in humans ().Retrospective analyses of four separate cohorts of women receiving adjuvant tamoxifen showed that women with … how do people use usenet to watch moviesWeb生物活性 for (Z)-4-Hydroxytamoxifen(Z)-4-Hydroxytamoxifen is an estrogen receptor antagonist (IC 50 = 27 μM).(Z)-4-Hydroxytamoxifen is a Tamoxifen (Cat. No. 0999) … how do people use the murray riverWeb4-Hydroxytamoxifen is the active metabolite of tamoxifen and a selective estrogen receptor (ER) modulator that is widely used in the therapeutic and chemopreventive treatment of … how do people use wave rockWebα-Hydroxytamoxifen is a metabolite of tamoxifen, reacts with DNA in the absence of metabolizing enzymes, and causes formation of DNA adducts [1] . Room temperature in … how much ram does the dsi haveWeb4-Hydroxytamoxifen 4-羟基他莫昔芬 (Z)-4- (1- [4- (二甲基氨基乙氧基)苯基]-2-苯基-1-丁烯)苯酚 它是雌激素受体拮抗剂 解析看不懂？ 免费查看同类题视频解析 查看解答 相似问题 … how do people use uranium