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Morphine Equivalent Dose (MED) – Opioid Conversions
WebMorphine Pur agoniste µ, κ et δ Principal alcaloïde de l’opium = latex du pavot somnifère Utilisé depuis IIIe siècle av JC, isolé en 1804 Un des analgésiques les plus utilisés au monde pour traiter des douleurs intenses Chez l’homme Pic plasmatique 45min par voie orale Biodisponibilité 30% orale, 50% SC Demi-vie 2-3h Métabolisation hépatique … WebDose: 5-10 mg IR PO q4h prn; Info: for use in palliative care; start 2.5-5 mg IR PO q4h prn in opioid-naive or opioid-nontolerant pts, may incr. dose by 25-50% q24h; individualize dose based on current opioid intake [parenteral route] Dose: 2-10 mg SC/IV q4h prn; Info: for use in palliative care; individualize dose per current opioid intake denim midi skirts with stretch waist
Route of morphine administration modulates conditioned …
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