Web18 gen 2024 · A total of 57 active compounds and 203 targets of SMS were identified by the TCMSP and DrugBank database, while 1791 OA-related targets were collected from the Genecards, OMIM, DisGeNet, TTD, and PharmGKB databases. By Venn analysis, 108 intersection targets between SMS targets and OA targets were obtained. Most of these ... WebPreDC is a database of predicted and experimentally determined drug combinations. PreDC collects 1,571 known drug combinations spanning 951 drugs, which are compiled from three localities: the Drug Combination Database (DCDB), the therapeutic target database (TTD) and literature. The database also contains 8,686 predictions that are considered ...
TCMSP - Traditional Chinese Medicine Systems Pharmacology …
Web25 gen 2024 · Methods: The quality control and identification of bioactive compounds of the GZD were carried out by using ultra-performance liquid chromatography (UPLC), and their OA-related genes were identified through overlapping traditional Chinese medicine systems pharmacology database (TCMSP), DrugBank and SEA Search Server databases, and … Web7 gen 2024 · TCMSP, DrugBank, Swiss Target Prediction were utilized to search the active components and effective targets of HQD. Ulcerative colitis effective targets were obtained by microarray data from the GEO database (GSE107499). Co-targets between HQD and ulcerative colitis are obtained by Draw Venn Diagram. fountain blue myrtle beach sc
在寻找疾病靶点方面,drugbank和TTD等数据库有何区别? - 知乎
Web7 gen 2024 · Combined microarray analysis, network pharmacology, and molecular docking for revealing the therapeutic targets and molecular mechanism of HQD against ulcerative … WebDrugBank’s DDI checker allows for up to 5 drugs at a time to be checked against one another for potential drug-drug interactions. For any interactions uncovered, the culprit drug pair is provided alongside a relative severity level: minor. moderate. major. And a concise description of the interaction. Web15 lug 2024 · After comprehensive analysis of TCMSP, DrugBank, and CTD databases by the key words of “Achyranthes bidentata” and “osteoarthritis”. A total of 26 target proteins of quercetin related to the osteoarthritis were obtained, mainly enriched in the mitochondrial ATP synthesis coupled proton transport, cellular response to estradiol stimulus, and nitric … disciples rock band