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Webb1 mars 2010 · Introduction. TNF-α is a potent pro-inflammatory cytokine exerting pleiotropic effects on various cell types and plays a critical role in the pathogenesis of chronic inflammatory diseases, such as RA [1, 2].Accumulating evidence suggests that not only soluble TNF-α, but also its precursor form, transmembrane TNF-α, is involved in the … WebbThe primary role of TNF is in the regulation of immune cells. TNF, as an endogenous pyrogen, is able to induce fever, apoptotic cell death, cachexia, and inflammation, inhibit tumorigenesis and viral replication, and respond to sepsis via IL-1 and IL-6 -producing cells. trackdown tv western
The North Face Wasatch Sleeping Bag 20°F/ -7°C - Unisex
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